Assay Bank
Lotus Labs has developed and validated over 500 bio analytical methods for leading pharmaceutical companies in India and abroad.
A partial list of our therapeutic experience in bio-availability and bio-equivalence studies.
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
A
| Abacavir
Abiraterone (in presence of Abiraterone Sulphate and N-oxide Abiraterone sulphate) Abiraterone (in presence of Abiraterone Sulphate and N-oxide Abiraterone sulphate) Abiraterone (in presence of Abiraterone Sulphate and N-oxide Abiraterone sulphate) Acetyl cysteine (Total) Acyclovir Acetyl salicylic acid (Aspirin) Acetylsalicyclic acid (in presence of Salicylic acid, Clopidogrel and Clopidgrel carboxylic acid) Acetylsalicyclic acid+Salicylic acid Acamprosate (Acetyl homotaurine) Afatinib Agomelatine Alprazolam Alfuzosin Almotriptan Alitretinoin Albuterol (Higher CC range) Albuterol Allopurinol Alogliptin Amlodipine + Valsartan Amlodipine Amlodipine (in presence of Candesartan, Atorvastatin and metabolites) Amlodipine (in presence of Peridopril, Perindoprilat, Indapamide) Amodiaquine + N-desethyl amodiaquine Amifampridine Amiodarone Amitriptylline + Nortriptylline Amitriptyline (inpresence of Nortriptyline) Amisulpride Ambrisentan
Ambroxol Amphotericin B (Free) Free Amphotericin B (In presence of pheniramine, dexamethasone, paracetamol) Liposomal Encapsulated Amphotericin B Total Amphotericin B Anastrozole Apixaban Apremilast Apremilast (Higher CC range) Aprepitant Atenolol Aripiprazole + Dehydro Aripiprazole Aripiprazole Artemether + Dihydroartimisinin Artesunate + Dihydroartimisinin Armodafinil Atorvastatin + Metabolites Atovaquone Atazanavir Atazanavir + Ritonavir Atazanavir + Cobicistat Atomoxetine Axitinib Axitinib Azithromycin Azithromycin (Lower CC range) Azacitidine (Higher CC range) Azacitidine Azilsartan (in presence of O-desethyal azilsartan M-II metabolite)
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B
Barnidipine
Bazedoxifene + Bazedoxifene-5-Glucuronide in presence of conjugated estrogens Baclofen R-Baclofen / Arbaclofen R-Baclofen / Arbaclofen (in presence of S-Baclofen) R and S-Baclofen Bendroflumethiazide Betahistine (in presence of 2-Pyridylacetic acid) Bezafibrate Bisoprolol
Bicalutamide Bosentan Brexpiprazole Bupropion and its metabolites (in presence of Dextromethorphan and Dextrorphan) Bupropion and its metabolites (in presence of Naltrexone) Budesonide in presence of 16 α Hydroxyprednisolone & Formoterol Beclomethasone-17-mono propionate + Beclomethasone dipropionate (in presence of formeterol) Beclomethasone 17 mono propionate +Beclomethasone dipropionate (Low LLOQ BMP)
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C
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Cabozantinib
Caffeine (in presence of Paracetamol + Ascorbic acid + Chlorpheniramine) Canagliflozin Calcifediol (Serum) Calcifediol (Surrogate matrix) Carvedilol + 4 Hydroxy Phenyl Carvedilol Candesartan Candesartan + HCTZ Candesartan + Nifedipine Candesartan (in presence of Amlodipine, Atorvastatin and metabolites) Capmatinib Captopril Carbocisteine Carbamazepine Carbidopa + Levodopa Celecoxib Chlorpheniramine R & S (in presence of Paracetamol + Ascorbic acid + Caffeine) Chlorzoxazone Clopidogrel Clopidogrel (in presence of Clopidogrel carboxylic acid, Aspirin and SA) Clopidogrel Carboxylic Acid Clonidine
Clarithromycin Clarithromycin + Clofazimine + Rifabutin (in presence of 14-Hydroxy Clarithromycin) Cefixime Cefprozil (Cis and Trans) Cetrizine Cefuroxime Cefditoren Ceftibuten Ceritinib Cinnarizine Cinacalcet Ciprofloxacin Citric acid Citric acid (in presence of Potassium) S-Citalopram (Chiral method) Cotrimoxazole (Sulfamethoxazole +Trimethoprim) Cyclosporine Cyclosporine Cyamemazine Cysteamine
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D
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Dabigatran (Non-conjugated) in presence of DAG
Dabigatran (Non-conjugated) in presence of DAG and Pantoprazole Dalfampridine Dapsone Dapsone in presence of N-Acetyl Dapsone Dilution Darifenacin Dasatinib 21-Desacetyl Deflazacort Desvenlafaxine Dexlansoprazole Dexketoprofen Desloratadine Dextromethorphan + Dextrorphan Dextromethorphan (in presence of Dextrorphan, Bupropion and metabolites) Desipramine Dicloxacillin Diclofenac Diclofenac (for gel formulation) Dicycloverine / Dicyclomine Diltiazem + Metabolites
Dipyridamol Dronedarone + Desbutyl dronedarone Donepezil Donepezil + 6-O-Desmethyl Donepezil Donepezil + Solifenasin (in presence of Ondansetron 400ng/mL) Doxazosin Doxepin + Nordoxepin Doxorubicin (Free) + Doxorubicinol Doxorubicin (Liposomal Encapsulated) - LED Doxorubicin (Total) in presence of Doxorubicinol Doxycycline Docetaxel (Total) Docetaxel (Unbound) Dolutegravir Domperidone Dodecyl Maltoside Droxidopa Dutasteride Duloxetine
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E
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Ebastine +Carebastine
Edoxaban Eletriptan Free Eicosapentaenoic Acid Total Eicosapentaenoic Acid Epinephrine Ethyl Eicosapentaenoate Eicosapentaenoic acid + Docosahexaenoic acid Entacapone Entecavir Eprosartan Ethambutol Unconjugated Estrone + Equilin Unconjugated Estrone + Unconjugated Equilin (in presence of 4 metabolites) Unconjugated Estrone + Unconjugated Equilin (in presence of 4 metabolites & Medroxyprogesterone acetate) Unconjugated Estrone + Unconjugated Equilin (in presence of 4 metabolites & Bazedoxifene and Bazedoxifene-5-glucuronide) Unconjugated Estrone + Norethindrone (in presence Estrone Sulfate, Estrone Glucuronide, Elagolix & Estradiol) Unconjugated Estrone (in presence of Progestrone and Estrone metabolites) Unconjugated Estrone (in Presence of Equilin, Estradiol and metabolites 8,9-Dehydroestrone, 17ß-dihydroequilin and 17ß-delta 8,9 Dehydro Estradiol) Unconjugated estrone +Norethrendrone (in presence of Elagolix, Estradiol, Estrone glucuronide, Estrone sulphate) Unconjugated Estradiol (in Presence of Elagolix, Estrone, Estrone glucuronide, Estrone sulphate, Norethindrone) Esomeprazole Esomeprazole Esomeprazole (Serum) Eszopiclone in presence of R-Zopiclone Efavirenz Empagliflozin Emtricitabine Enalapril +Enalaprilat Enalapril (in presence of Enalaprilat, R & S-Lercanidipine)
Enzalutamide (in presence of N-desmethyl Enzalutamide) Enzalutamide + N-desmethyl Enzalutamide Erythromycin (Higher CC range) Total Erythromycin (Erythromycin ethyl succinate) Free Erythromycin (Erythromycin ethyl succinate) Ethacrynic acid Ethinyl Estradiol Ethinyl Estradiol in presence of Norgestimate and 17 Desacetyl Norgestimate Ethinyl Estradiol in presence of Etonogestrel Ethinyl Estradiol (in presence of Levonorgestrel) Ethinyl Estradiol + Norethindrone Ethinyl Estradiol (in presence of Norethindrone) Ethinyl Estradiol in presence of Norelgestromin Ethinyl Estradiol in presence of desogestrol Etoricoxib Eszopiclone Erlotinib Estradiol (in presence of Estrone and Norethindrone) Estradiol (in presence of Estrone and Estrone sulfate) Total Estradiol (in presence of Estrone and Equiline) Everolimus Exemestane Ezetimibe (Free / Unconjugated) in presence of ezetimibe phenoxy glucuronide Ezetimibe (Free) (unconjugated) + Atorvastatin+Ortho Hydroxy Atorvastatin + Para Hydroxy Atorvastatin Ezetimibe (Total) Total Ezetimibe in presence of Atorvastatain and its metabolites Ezetimibe (Unconjugated) + Ezetimibe Phenoxy Glucuronide
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F
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Famotidine
Febuxostat Felbamate Felodipine Fenofibric Acid Fesoterodine [5-hydroxymethyl tolterodine (5-HMT)] Fexofenadine Fingolimod+Fingolimod Phosphate Finasteride Finerenone
Fidaxomicin (in presence of Fidaxomicin metabolite OP-1118) Formoterol (in presence of Budesonide & 16-α hydroxyprednisolone) Formoterol (in presence of Mometasone) Formoterol (in presence of Beclomethasone and metabolite) Fluconazole Fluoxetine + Norfluoxetine
Fluoxetine (in presence of Norfluoxetine) Fluticasone Furoate (in presence of Vilanterol) Fluticasone Propionate + Salmeterol Fluticasone Propionate in presence of Azelastine Fluticasone Propionate in presence of Azelastine(Low LLOQ 0.2 pg/ml) Fluticasone Propionate (low range-0.2 pg/ml) Fluticasone Propionate (low range-0.5 pg/ml) Fluticasone Propionate (in presence of Salmeterol) Fluticasone Propionate (in presence of Albuterol) Fluticasone Furoate (0.15 pg/ml) Fluticasone Furoate (in presence of Umeclidinium & Vilanterol) Furosemide
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G
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Granisetron
Galantamine Gabapentin Gabapentin (LLOQ-5ng/mL) Gliclazide Glipizide Glibenclamide Glibenclamide + Metformin Glimiperide
Gefitinib in presence of O-desmethyl gefitinib Gefitinib + O-desmethyl gefitinib Gemfibrozil (in presence of 1-O-β-glucuronide) Glycopyrrolate in presence of Indacetrol Guanfacine Guaifenesin GRC27864+GRC27884
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H
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Haloperidol
Haloperidol (in presence of benztropine) Hydrochlorothiazide Hydrochlorothiazide in presence of Nebivolol
Hydroxychloroquine N-Butyl Hyoscine
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I
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Isoprinosine(P-aminobenzoic acid+Dimethyal-2-propanol inpresence of Isonosine)
Ibrutinib (in presence of PCI-45227) Ibrutinib (in presence of dihydrodiol Ibrutinib (PCI-45227)) Irbesartan Irbesartan + HCTZ Ibuprofen (R and S) Ibuprofen Imipramine + Desipramine Imatinib + Desmethyl Imatinib Indapamide in presence of Peridopril and Perindoprilat Indacaterol (in presence of Glycopyrrolate) Indapamide (in presence of Peridopril, Perindoprilat, Amlodipine) Indomethacin
Indomethacin+Methocarbamol (in presence of Betamethasone) Ipratropium Irinotecan Irinotecan active metabolite (SN-38) Isotretinoin (in presence of 4-oxo isotretinoin) Ivabradine Ivacaftor Tezacaftor+Ivacaftor (in presence of M1 and M6 metabolite) Ivermectin Ivermectin B1b
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J
K
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Ketorolac
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L
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Lacidipine
Lacosamide in presence of Desmethyl lacosamide Lamotrigine Lamivudine Lamivudine + Stavudine Lamivudine + Zidovudine + Nevirapine Lamivudine + Zidovudine Lamivudine + Stavudine + Nevirapine Lansoprazole Lapatinib (Higher range) Labetalol Lenalidomide Lenvatinib R & S Lercanidipine R & S Lercanidipine (in presence of Enalapril and Enalaprilat) S Lercanidipine Levetiracetam Levocetrizine Levodopa (in presence of carbidopa)
Levofloxacin Letrozole Levonorgestrel Levothyroxine (Total) - BSA Liothyronine (Total) Lipoic Acid Losartan + Losartan Carboxy Acid Loratadine Loperamide Lisinopril Linezolid 15-Hydroxy Lubiprostone Lurasidone (in presence Lurasidone Metabolite ID-14326 + Lurasidone Metabolite ID-14283) Lurasidone Metabolite ID-14326 + Lurasidone Metabolite ID-14283 Lumefantrine Lopinavir+Ritonavir
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M
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Macitentan (in presence of N-Despropyl Macitentan metabolite)
Medroxyprogesterone Acetate (in presence of Estrone and Equilin Melatonin Meloxicam Mirtazapine Minocycline Mifepristone + Metabolites Mirabegron Mirabegron + Solifenacin Misoprsotol acid Metaxalone Metoprolol Metformin Mesalamine (in presence of N-acetyl mesalamine) Mesalamine (in presence of N-acetyl mesalamine) Mesalamine (in presence of N-acetyl mesalamine)
Methenamine Methylnaltrexone Metoclopramide Memantine Midodrine (in presence of Desglymidodrine) Migalastat Modafinil Molindone Montelukast Moxifloxacin Moxonidine Moexipril Monomethyl Fumarate
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N
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Naproxen
Naratriptan Nebivolol Nebivolol (in presence of HCTZ) Nefopam Nevirapine Niacin + Nicotinuric Acid Nimesulide + 4-OH Nimesulide Nifedipine Nisoldipine + 4-Hydroxy Nisoldipine Nicotine
Nicorandil Nilotinib Nitrofurantoin Norethindrone (in presence of Estrone and Estradiol) Norethindrone (in presence of Ethinyl Estradiol) Norgestrel in presence of Ethinyl estradiol, Norgestime and 17 desacetyl norgestimate Nortriptyline Nortriptyline + 10-Hydroxy Nortriptyline
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O
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Octreotide (Fast & Fed)
Octreotide (Rabbit Plasma) Oxcarbazepine + 10, 11-Dihydro-10-Hydroxycarbamazepine (MHD) Oxybutynin (in presence of N-desethyl Oxybutynin) Oxybutynin + N-Desethyl Oxybutynin Omeprazole Oxybutynin+Pilocarpine+Ndesethyl oxybutynin Olanzapine
Olmesartan Olmesartan + HCTZ Olmesartan + HCTZ+Amlo Ondansetron Oseltamivir
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P
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Paclitaxel (Total)
Paclitaxel (Unbound) Paliperidone Pantoprazole Pazopanib Paroxetine Paracetamol Paracetamol (in presence of Caffeine + Ascorbic acid + Chlorpheniramine) Paracetamol (in presence of phenylephrine) Paracetamol (in presence of carbinoxamine and phenylephrine) Perindopril + Perindoprilat (in presence of Indapamide, Amlodipine) Phenylephrine (in presence of Paracetamol) Phenylephrine + Carbinoxamine (in presence of Paracetamol) Phenytoin Pimavanserin Pioglitazone+Metabolites Pioglitazone Pirfenidone (in presence of 5-carboxy-pirfenidone metabolite 10µg/mL)
Pitavastatin Pomalidomide Potassium citrate (using Stripped Urine as surrogate matrix) Potassium chloride (using Stripped Urine as surrogate matrix) Pramipexole Prasugrel R-95913 (Inactive) Prasugrel R-138727 MP (Active) in presence of Prasugrel R-95913 Pravastatin Pregabalin Prednisolone in presence of Prednisone Progesterone Progesterone (in presence of Estradiol and Estrone) Phytonadione (Trans+Cis) 2-Pyridylacetic acid Pyridostigmine
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Q
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Quetiapine
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R
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Rasagiline
Rabeprazole Ranolazine Ranitidine Ramipril+Ramiprilat Raloxifene Raloxifene 4 Glucuronide + Raloxifene 6 Glucuronide Rebamipide Relugolix Remogliflozin Etabonate + Remogliflozin + GSK279782 (in presence of metformin Repaglinide Rifabutin Rifampin Rifaximin Riluzole Rilpivirine Risperidone
Risperidone + Paliperidone Ritonavir Rizatriptan Rizatriptan + N-monodesmethyl Rizatriptan + Triazalomethyl-indole-3-acetic acid meatbolites Rivaroxaban Rivaroxaban (lower range) Rivastigmine Rufinamide Roflumilast in presence of Roflumilast-N-oxide Rosiglitazone Rotigotine Ropinirole Rosuvastatin Rosuvastatin (in presence of Valsartan) Rosuvastatin + Valsartan
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S
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Sacubitril + Valsartan (in presence of Sacubitril metabolite LBQ-657)
Sacubitril metabolite LBQ-657 (in presence of Sacubitril + Valsartan) Salmeterol in presence of fluticasone propionate (lower LLOQ) Sapropterin (tetra hydrobiopterin) Scopolamine Sertraline (in presence of Desmethyl Sertraline) Semaglutide Sildenafil (in presence of N-desmethyl sildenafil) Sildenafil & N-Desmethyl Sildenafil Silodosin (in presence of Silodosin glucuronide conjugate KMD-3213G) Simvastatin+Simvastatin Hydroxy acid Simvastatin (in presence of Simvastatin Hydroxy acid) Sibutramine+Monodesmethyl Sibutramine +Didesmethyl Sibutramine
Sirolimus Sitagliptin Sitagliptin+Metformin Sofosbuvir (in presence of GS-331007) Solifenacin Sorafenib Sulpiride Sumatriptan Sumatriptan (for nasal spray) Sunitinib
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T
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Tacrolimus
Tadalafil Tafamidis Tamsulosin Tasimelteon Terazosin Terbinafine Teriflunomide Telmisartan Telmisartan + Hydrochlorthiazide Testosterone (serum) Testosterone (plasma) Testosterone Undecanoate (in presence of Testosterone) Tetracycline Theophylline Ticagrelor + AR-C124910XX (Desethoxyhydroxy Ticagrelor) Tiotropium (low range) Tizanidine Tenofovir Tofacitinib
Torsemide Tolterodine + 5-hydroxymethyl tolterodine (5-HMT) Total Iron Trandolapril+Trandolaprilat Trazadone Trazadone (in presence of m-chlorophenyl piperazine) Triamcinolone Acetonide Tramadol Tramadol+ O-Desmethyl Tramadol (ODT) Tramadol (in presence of O-Demethyl Tramadol) Trametinib Trametinib Transferrin Bound Iron Treprostinil Trospium Trimebutine+ N Desmethyl Trimebutine Topiramate
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U
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Ubrogepant
Ulipristal acetate (in presence of Ulipristal acetate oxidative metabolite PGL4002) Ursodiol (Unconjugated) Ursodiol + GDCA + TDCA
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V
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Valproic Acid
Venlafaxine (in presence of O-desmethyl venlafaxine) Venlafaxine (in presence of O-desmethyl venlafaxine & ondansetron) Venlafaxine (in presence of O-desmethyl venlafaxine & Domperidone) Venlafaxine + O-Desmethyl Venlafaxine Venlafaxine + O-Desmethyl Venlafaxine (in presence of ondansetron) Valacyclovir Valacyclovir + Acyclovir Vardenafil Valsartan Valsartan + HCTZ
Valganciclovir+ Ganciclovir Vigabatrin Voriconazole Vortioxetine Vilanterol (in presence of Fluticasone furoate) Vilazodone Vildagliptin Vildagliptin +Metformin
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W
X
Y
Z
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Zaleplon
Ziprasidone Zilueton Zonisamide Zoledronic acid
Zolpidem Zopiclone + Zopiclone N-oxide
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